Table of Contents Author Guidelines Submit a Manuscript
Journal of Ophthalmology
Volume 2012, Article ID 576394, 9 pages
Review Article

Glaucoma and Corneal Transplant Procedures

1Department of Ophthalmology, Ministry of Health, Manama 12, Bahrain
2Division of Anterior Segment, King Khaled Eye Specialists Hospital, Riyadh 11462, Saudi Arabia
3Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA

Received 1 August 2011; Accepted 10 October 2011

Academic Editor: G. L. Spaeth

Copyright © 2012 Ammar M. Al-Mahmood et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Glaucoma after corneal transplantation is a leading cause of ocular morbidity after penetrating keratoplasty. The incidence reported is highly variable and a number of etiologic factors have been identified. A number of treatment options are available; surgical intervention for IOP control is associated with a high incidence of graft failure. IOP elevation is less frequently seen following deep anterior lamellar keratoplasty. Descemet's striping-automated endothelial keratoplasty is also associated with postprocedure intraocular pressure elevation and secondary glaucoma and presents unique surgical challenges in patients with preexisting glaucoma surgeries. Glaucoma exists in up to three-quarters of patients who undergo keratoprosthesis surgery and the management if often challenging. The aim of this paper is to highlight the incidence, etiology, and management of glaucoma following different corneal transplant procedures. It also focuses on the challenges in the diagnosis of glaucoma and intraocular pressure monitoring in this group of patients.