Clinical Study

Adverse Effects of Systemic Immunosuppression in Keratolimbal Allograft

Table 1

Oral immunosuppression therapy regimen.

ClassStarting doseMedicationNumber of patientsAvg. duration (months)

Corticosteroid1 mg/kg/dayPrednisone1612.8 (Median:10, Range: 3–25)
Calcineurin inhibitor3-4 mg/kg/dayCyclosporine413.7 (Range: 4–19)
2–4 mg BIDTacrolimus1017.8 (Range: 5–25)
Antimetabolite100–150 mg/dayAzathioprine25.7 (Range: 1–16)
500–1000 mg BIDMycophenolate mofetil1216.9 (Range: 5–39)
IL-2 inhibitor2 mg/daySirolimus122