Comparison of Newly Diagnosed Ocular Hypertension and Open-Angle Glaucoma: Ocular Variables, Risk Factors, and Disease Severity

Table 2

Summary of ocular examination findings.

Variable	OAG	OH	Mean Difference^a	𝑃-value^b
	𝑁=292	𝑁=113	(95% CI)
Mean Intraocular pressure ±SD, mmHg^c	20.5±5.2	23.4±3.3	−2.9 (−3.7, −2.0)	<0.0001
Mean central corneal thickness ±SD, microns^d	554.2±38.2	583.4±34.6	−29.1 (−36.9, −21.4)	<0.0001
Mean visual acuity ±SD, LogMAR	0.2±0.2	0.1±0.2	0.1 (0.0, 0.1)	<0.001
Mean spherical equivalence ± SD, diopters^e	−1.3±3.3	−0.6±2.5	−0.7 (−1.3, −0.0)	0.038
Abnormal anterior segment examination, 𝑛 (%)^f	19 (6.5)	10 (8.9)	0.7 (0.3, 1.6)	0.404
Presence of relative afferent pupillary defect, 𝑛 (%)^f	18 (6.2)	0 (0.0)	Infinite (Infinite)	0.005
Myopia, 𝑛 (%)^g	135 (46.2)	46 (40.7)	1.3 (0.8, 1.9)	0.316

Abbreviations: CI: confidence interval; LogMAR: logarithm of the minimum angle of resolution; n: number of subjects; OAG: open-angle glaucoma; OH: ocular hypertension; SD: standard deviation.
^aMean difference calculated as OAG−OH.
^bSignificance of differences between the OAG and OH groups was tested using the chi-square test for categorical data and the t-test for continuous data. Fisher’s exact test was used for categorical data when the expected marginal size was <5.
^cMissing data for 1 subject in the OH group.
^dMissing data for 1 subject in the OAG group.
^e𝑛=266 in the OAG and 𝑛=100 in the OH group.
^fMissing data for 1 subject in both the OAG and OH groups.
^gData concerning myopia were collected under medical history.