Journal of Ophthalmology / 2013 / Article / Tab 2

Research Article

RNA Interference Targeting Connective Tissue Growth Factor Inhibits the Transforming Growth Factor-β2 Induced Proliferation in Human Tenon Capsule Fibroblasts

Table 2

Effect of CTGF-siRNA on cell cycle of HTFs.

GroupG0/G1 (%)S (%)G2/M (%)

Control
TGF- (+)
CTGF-siRNA + TGF- (+)
Control siRNA + TGF- (+)

Serum starved HTFs were transfected with CTGF-siRNA or control siRNA before being stimulated with TGF- for 48 h. Flow cytometry was used to analyze the effect of CTGF-siRNA on cell cycle (G0/G1, S, G2/M phase) after various treatments. Data were from three experiments. versus control group, versus TGF- (+) group.

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