Clinical Study

Diagnostic Validity of Clinical Signs Associated with a Large Exophoria at Near

Table 4

Diagnostic validity for each test using cut-offs obtained with ROC curves.

TestCut-off with ROC curveSensitivity
(CI 95%)
Specificity
(CI 95%)
LR+  
(CI 95%)
LR−   
(CI 95%)

NPC recovery≥8.25 cm0.85
(0.69–1)
0.82
(0.61–1)
4.79
(1.69–14)
0.19
(0.08–0.48)
BAF≤8.25 cpm0.88
(0.75–1)
0.79
(0.63–0.94)
4.14
(2.12–8.09)
0.15
(0.06–0.39)
NPC break≥5.35 cm0.73
(0.56–0.89)
0.91
(0.80–1)
8.00
(2.67–24)
0.30
(0.17–0.53)
MAF≤8.25 cpm0.70
(0.52–0.87)
0.94
(0.84–1)
12.00
(2.95–45)
0.32
(0.19–0.55)
VF≤14.75 cpm0.70
(0.52–0.87)
0.70
(0.52–0.87)
2.30
(1.31–4.04)
0.25
(0.25–0.76)
MEM≤0.63 D0.73
(0.56–0.89)
0.55
(0.36–0.73)
1.60
(1.04–2.46)
0.50
(0.26–0.95)
NRA≤2.38 D0.76
(0.60–0.92)
0.52
(0.33–0.70)
2.30
(1.31–4.04)
0.43
(0.25–0.76)

LR+: positive likelihood ratio, LR−: negative likelihood ratio, CI: confidence interval, NPC: near point of convergence, BAF: binocular accommodative facility, MAF: monocular accommodative facility, VF: vergence facility, MEM: monocular estimated method, NRA: negative relative accommodation, cpm: cycles per minute, D: diopter.