Clinical Study

Multimodal Imaging in Hereditary Retinal Diseases

Figure 2

Color photograph shows macular atrophy and retinal flecks in a Stargardt patient. OCT scans are illustrated by the arrows 1 and 2. The autofluorescent frame clearly delineates the retinal flecks. Thin and open arrows point to two of the flecks, respectively, crossed by scans 1 and 2. Fluorescein angiography shows the dark choroid appearance, and the hypofluorescent flecks are hardly discernable in the hyperfluorescent background because of RPE changes. On ICG, late phase (30 min), the hypofluorescent lesions appear more numerous than the autofluorescent flecks, and there is sparing of the peripapillary area. The SD-OCT scan in square A shows a small hyperreflective lesion located at the inner part of the RPE layer, called type 1 deposit, and macular atrophy. The SD-OCT scan in square B shows a small hyperreflective linear lesion located at the level of the outer nuclear layer and clearly distinguished from the RPE layer, called type 2 deposit.
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