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Journal of Ophthalmology
Volume 2013, Article ID 767931, 4 pages
Clinical Study

Cental Macular Thickness in Patients with Type 2 Diabetes Mellitus without Clinical Retinopathy

1Department of Ophthalmology, Sisli Etfal Training and Research Hospital, Istanbul, Turkey
2Sisli Etfal Hastanesi, Halaskargazi Caddesi Etfal Sokak No. 10, 34400 Sisli, Istanbul, Turkey
3Department of Endocrinology, Namık Kemal University, Tekirdag, Turkey

Received 9 December 2012; Accepted 13 March 2013

Academic Editor: Andrew G. Lee

Copyright © 2013 Mehmet Demir et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To compare central macular thickness (CMT) of diabetic patients with type 2 diabetes without clinical retinopathy and healthy subjects. Materials and Methods. Optical coherence tomography (OCT) measurements were performed in 124 eyes of 62 subjects with diabetes mellitus without clinical retinopathy (study group: 39 females, 23 males; mean age: 55.06 ± 9.77 years) and in 120 eyes of 60 healthy subjects (control group: 35 females, 25 males; mean age: 55.78 ± 10.34 years). Blood biochemistry parameters were analyzed in all cases. The data for central macular thickness (at 1 mm), the levels of fasting plasma glucose, and glycosylated hemoglobin (HbA1c) were compared in both groups. Results. The mean central macular thickness was 232.12 ± 24.41 µm in the study group and 227.19 ± 29.94 µm in the control group. The mean HbA1c level was 8.92 ± 2.58% in the study group and 5.07 ± 0.70% in the control group ( ). No statistically significant relationship was found between CMT, HbA1c, and fasting plasma glucose level in either group ( ). Conclusions. Central macular thickness was not significantly thicker in patients with type 2 diabetes without clinical retinopathy than in healthy subjects.