Glaucoma Diagnostic Accuracy of Machine Learning Classifiers Using Retinal Nerve Fiber Layer and Optic Nerve Data from SD-OCT

Table 2

Mean ± standard deviation of SD-OCT parameters in both groups.

SD-OCT	Healthy (𝑛=46)	Glaucoma (𝑛=57)	𝑃
Average thickness (µm)	93.3±9.9	81.4±11.2	<0.001
Quadrant (µm)
Temporal	63.2±11.3	57.4±12.5	0.017
Superior	117.4±15.1	100.4±18.9	<0.001
Nasal	72.8±10.9	66.4±9.8	0.002
Inferior	119.9±17.6	101.1±17.5	<0.001
Clock hour (µm)
1	103.3±19.0	90.9±20.8	0.002
2	90.9±16.2	78.7±13.8	<0.001
3	61.4±9.3	59.4±9.5	0.295
4	66.2±13.7	62.1±11.7	0.105
5	97.2±18.9	88.0±15.6	0.007
6	132.4±26.4	111.1±25.3	<0.001
7	130.2±23.4	104.3±27.8	<0.001
8	64.7±13.5	58.4±15.7	0.033
9	50.8±14.5	48.1±12.8	0.316
10	74.2±13.6	65.9±14.4	0.003
11	123.8±21.9	103.2±26.7	<0.001
12	125.0±26.1	107.0±25.6	<0.001
Cup/disc area (ratio)	0.34±0.14	0.53±0.13	<0.001
Average cup/disc (ratio)	0.56±0.13	0.71±0.09	<0.001
Vertical cup/disc (ratio)	0.53±0.13	0.68±0.09	<0.001
Rim area (mm^2)	1.28±0.21	0.98±0.24	<0.001
Cup volume (mm^3)	0.24±0.24	0.50±0.29	<0.001
Disc area (mm^2)	2.01±0.41	2.19±0.52	0.055

SD-OCT: spectral domain optical coherence tomography.