Novel Lutein Loaded Lipid Nanoparticles on Porcine Corneal Distribution

Table 2

Summary of corneal lutein delivery using CD combined with NLCs.

Vehicles	Lutein content; (μg/g)	Accumulation rate; (μg/g/hr)	Partition coefficient; (10^−3)	Enhance ratio
NLC	2000	10.6 ± 0.4	21.25 ± 0.8	1
NLC + 0.5% HPβCD	2000	19.8 ± 0.2	39.8 ± 0.55	1.80
NLC + 1% HPβCD	2000	23 ± 1.8	46 ± 3.7	2.17
NLC + 2% HPβCD	2000	52.3 ± 5	104.6 ± 9	4.92
NLC + 3% HPβCD	2000	27 ± 1.6	54.2 ± 3.2	2.55
NLC + 2% HPβCD	4000	142.8 ± 3.0	142.8 ± 5.7	13.44