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Journal of Ophthalmology
Volume 2014, Article ID 402193, 6 pages
Research Article

Impaired Corneal Biomechanical Properties and the Prevalence of Keratoconus in Mitral Valve Prolapse

1Department of Ophthalmology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, Turkey
2Department of Cardiology, Ankara Ataturk Training and Research Hospital, Yildirim Beyazit University, 06810 Ankara, Turkey

Received 16 February 2014; Revised 26 March 2014; Accepted 31 March 2014; Published 17 April 2014

Academic Editor: Antonio Queiros

Copyright © 2014 Emine Kalkan Akcay et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To investigate the biomechanical characteristics of the cornea in patients with mitral valve prolapse (MVP) and the prevalence of keratoconus (KC) in MVP. Materials and Methods. Fifty-two patients with MVP, 39 patients with KC, and 45 control individuals were recruited in this study. All the participants underwent ophthalmologic examination, corneal analysis with the Sirius system (CSO), and the corneal biomechanical evaluation with Reichert ocular response analyzer (ORA). Results. KC was found in six eyes of four patients (5.7%) and suspect KC in eight eyes of five patients (7.7%) in the MVP group. KC was found in one eye of one patient (1.1%) in the control group ( ). A significant difference occurred in the mean CH and CRF between the MVP and control groups ( and , resp.). All corneal biomechanical and topographical parameters except IOPcc were significantly different between the KC-MVP groups ( ). Conclusions. KC prevalence is higher than control individuals in MVP patients and the biomechanical properties of the cornea are altered in patients with MVP. These findings should be considered when the MVP patients are evaluated before refractive surgery.