The Influence of Prior Hyperthyroidism on Euthyroid Graves’ Ophthalmopathy

Table 2

Difference in clinical presentation and severity of euthyroid Graves’ ophthalmopathy.

Clinical presentation	Group A; (𝑁=37)	Group B; (𝑁=41)	𝑃 Value
Unilateral disease	12 (32%)	13 (32%)	NS^†
Time interval onset thyroid-eye disease, median years (mean; range)	—	4 (8; 1–34)	—
Clinical activity score, mean (±SD^‡)	1 (±1)	2 (±1)	NS^†
Upper eyelid retraction, mean (±SD^‡)	1 mm (±1)	1 mm (±1)	NS^†
Hertel reading, mean (±SD^‡)	14 mm (±4)	16 mm (±4)	0.028
Extraocular muscle involvement
Normal eye motility	17 (46%)	9 (22%)	0.032
NOSPECS class 4 grade a	16 (43%)	22 (54%)	NS^†
NOSPECS class 4 grade b	4 (11%)	10 (24%)	NS^†
Severity
Mild	14 (38%)	12 (29%)	NS^†
Moderate-to-severe	23 (62%)	28 (68%)	NS^†
DON^§	0 (0%)	1 (2%)	NS^†

Values are expressed as numbers, except as if indicated.
^†NS = not significant.
^‡SD = standard deviation.
§DON = dysthyroid optic neuropathy.