Table 2: CST parameter before and 3months after CXL.

Parameter (unit)Before CXL3 months after CXL
Min/MaxMedian (Q25/Q75)Mean (±SD)Min/MaxMedian (Q25/Q75)Mean (±SD)

IOP (mmHg)177.50/17.0011.00 (9.00/12.50)11.26 (2.76)178.00/45.5014.00 (12.00/16.00)15.12 (8.31)0.004
pachy (µm)17415/562487 (473/539)498 (42.99)17365 /548452 (438 /502)463 (45.33)<0.001
defampmax (mm)170.94/1.411.18 (1.08/1.26)1.16 (0.13)170.44/1.511.09 (1.04/1.21)1.10 (0.22)0.155
A1time (ms)176.49/7.506.93 (6.78/7.13)6.96 (0.28)176.61/10.687.12 (6.87/7.35)7.29 (0.92)0.024
A1length (mm)171.33/1.891.70 (1.53/1.79)1.65 (0.18)171.22/1.861.69 (1.60/1.76)1.64 (0.18)0.891
A1velocity (ms)170.09/0.220.14 (0.13/0.17)0.15 (0.04)170.03/0.220.15 (0.13/0.17)0.15 (0.05)0.902
A2time (ms)1721.41/22.8622.25 (21.84/22.46)22.16 (0.46)1619.07/22.9321.65 (21.54/21.95)21.66 (0.83)0.039
A2length (mm)170.80/2.411.27 (1.09/1.87)1.43 (0.47)170.78/2.121.55 (1.08/1.82)1.49 (0.44)0.702
A2velocity (ms)17−0.67/−0.26−0.46 (−0.52/−0.39)−0.45 (0.11)16−0.57/−0.24−0.44 (−0.49/−0.34)−0.42 (0.10)0.348
hctime (ms)1716.17/18.2517.09 (17.09/17.56)17.27 (0.50)1715.25/18.7117.09 (16.63/17.56)17.04 (0.77)0.292
peakdist (mm)172.14/5.624.81 (4.68/5.10)4.46 (1.07)172.01/5.924.58 (2.49/5.08)3.97 (1.36)0.165
radius (mm)174.27/9.485.80 (5.25/6.29)6.04 (1.27)174.52/9.966.04 (5.25/6.56)6.21 (1.41)0.488
radius3p (mm)174.27/9.485.96 (5.30/6.35)6.12 (1.28)174.52/9.966.04 (5.25/6.56)6.23 (1.43)0.683
A1deformationamp (mm)110.09/0.320.12 (0.10/0.15)0.14 (0.06)80.07/0.220.13 (0.11/0.18)0.14 (0.05)0.544
hcdeformationamp (mm)110.99/1.551.14 (1.05/1.33)1.19 (0.18)80.95/1.411.14 (1.07/1.25)1.16 (0.15)0.838
A2deformationamp (mm)110.18/0.530.38 (0.33/0.42)0.37 (0.09)70.21/0.440.38 (0.28/0.43)0.36 (0.08)0.270
A1deflectionlength (mm)111.85/3.152.30 (2.02/2.46)2.32 (0.36)71.55/2.892.33 (2.06/2.79)2.38 (0.48)0.612
hcdeflectionlength (mm)115.50/6.125.80 (5.75/6.03)5.85 (0.19)85.70/6.165.90 (5.78/5.96)5.89 (0.15)0.699
A2deflectionlength (mm)101.90/3.633.00 (2.51/3.09)2.85 (0.48)52.05/3.503.12 (3.04/3.31)3.00 (0.56)0.095
hcdeflectionamp (mm)110.81/1.360.97 (0.89/1.09)1.01 (0.17)110.75/1.360.97 (0.91/1.09)1.00 (0.17)0.592
A1deflectionamp (mm)110.07/0.310.10 (0.07/0.11)0.11 (0.07)110.04/0.470.10 (0.07/0.18)0.14 (0.12)0.188
A2deflectionamp (mm)110.03/0.330.13 (0.06/0.19)0.14 (0.09)110.00/0.690.15 (0.09/0.19)0.20 (0.20)0.247
deflectionampmax (mm)110.81/1.400.98 (0.92/1.09)1.02 (0.17)80.76/1.261.00 (0.93/1.13)1.02 (0.16)0.885
deflectionampmax (ms)1115.99/16.8316.40 (16.17/16.74)16.44 (0.31)814.35/17.2015.99 (15.89/16.38)16.01 (0.81)0.254

values reaching statistical significance are in bold font.
IOP: intraocular pressure; pachy: central corneal pachymetry; defampmax: maximum corneal deformation amplitude; A1time: time of the first applanation; A1length: Length of the first applanation; A1velocity: velocity of the corneal apex at the first applanation; A2time: time of the second applanation; A2length: length of the second applanation; A2velocity: velocity of the corneal apex at the second applanation; hctime: highest concavity, time of the maximum deformation; peakdist: distance between both non-deformed peaks; radius: radius of curvature at maximum deformation, calculated with “parabolic fit”; radius3p: radius of curvature at maximum deformation, 3-point-fit; A1deformationamp: deformation amplitude at the time of the first applanation; hcdeformationamp: deformation amplitude at the time of the highest concavity; A2deformationamp: deformation amplitude at the time of the second applanation; A1deflectionlength: deflection length at the time of the first applanation; hcdeflectionlength: deflection length at the time of the highest concavity; A2deflectionlength: deflection length at the time of the second applanation; hcdeflectionamp: deflection amplitude of the highest concavity; A1deflectionamp: deflection amplitude of the first applanation; A2deflectionamp: deflection amplitude of the second applanation; deflectionampmax (mm): maximum deflection amplitude; deflectionampmax (ms): time of the maximum deflection amplitude.
*Paired -test.
Differences are not normally distributed. Therefore, Wilcoxon matched-pairs test was used.