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Journal of Ophthalmology
Volume 2014 (2014), Article ID 852624, 5 pages
Clinical Study

Corneal Endothelial Cell Density and Morphology in Healthy Turkish Eyes

Department of Ophthalmology, Cerrahpasa School of Medicine, Istanbul University, Olgunlar Sokak No. 6/10, Bakirkoy, 34144 Istanbul, Turkey

Received 5 October 2013; Accepted 30 December 2013; Published 10 February 2014

Academic Editor: Terri L. Young

Copyright © 2014 Ceyhun Arıcı et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To describe the normative values of corneal endothelial cell density, morphology, and central corneal thickness in healthy Turkish eyes. Methods. Specular microscopy was performed in 252 eyes of 126 healthy volunteers (M : F, 42 : 84). Parameters studied included mean endothelial cell density (MCD), mean cell area (MCA), coefficient of variation (CV) in cell size, percentage of hexagonal cells, and central corneal thickness (CCT). Results. The mean age of volunteers was (range, 20 to 70) years. There was a statistically significant decrease in MCD ( ; correlation, −0.388) and percentage of hexagonal cells, ( ; correlation, −0.199) with age. There was also a statistically significant increase in MCA ( ; correlation, 0.363) with increasing age. There was no statistically significant difference in MCD, MCA, CV in cell size, percentage of hexagonal cells, and CCT between genders and there was also no significant difference in these parameters between fellow eyes of subjects. Conclusions. Normotive data for the endothelium in the Turkish population are reported. Endothelial cell density in the Turkish eyes is less than that described in the Japanese, American, Chinese, and Filipino eyes and higher than that described in Indian, Thai, and Iranian eyes.