Correlation between Optic Nerve Parameters Obtained Using 3D Nonmydriatic Retinal Camera and Optical Coherence Tomography: Interobserver Agreement on the Disc Damage Likelihood Scale
Table 2
Mean values derived from the optic nerve head ophthalmoscopic examination, disc damage likelihood scale, and optical coherence tomography according to diagnosis.
Normal
Glaucoma suspect
Glaucoma
value*
Post hoc analysis
Normal versus Glaucoma suspect
Normal versus Glaucoma
Glaucoma suspect versus Glaucoma
DDLS evaluated using 3D optic disc photography
0.58 ± 0.50
2.03 ± 0.66
4.23 ± 1.23
<0.001
<0.01
<0.001
<0.001
Ophthalmoscopic examination.
Horizontal C/D ratio
0.37 ± 0.10
0.61 ± 0.11
0.63 ± 0.18
<0.001
<0.001
<0.001
0.673
Vertical C/D ratio
0.38 ± 0.09
0.57 ± 0.13
0.59 ± 0.20
<0.001
<0.001
<0.001
0.590
3D optic disc photography
Vertical C/D ratio
0.48 ± 0.11
0.57 ± 0.03
0.64 ± 0.11
<0.001
<0.001
<0.001
<0.001
Superior rim width
0.45 ± 0.10
0.41 ± 0.08
0.32 ± 0.09
<0.001
0.182
<0.001
<0.001
Inferior rim width
0.47 ± 0.12
0.44 ± 0.10
0.36 ± 0.13
<0.001
0.361
<0.001
0.001
Cup area
0.68 ± 0.35
1.04 ± 0.20
1.38 ± 0.74
<0.001
<0.001
<0.001
0.005
Disc area
2.55 ± 0.55
3.17 ± 0.24
3.10 ± 0.89
<0.001
<0.001
0.002
0.657
Rim area
1.87 ± 0.35
2.09 ± 0.20
1.71 ± 0.41
<0.001
0.014
0.089
<0.001
C/D area ratio
0.25 ± 0.10
0.33 ± 0.65
0.42 ± 0.12
<0.001
0.002
<0.001
<0.001
Rim disc area ratio
0.74 ± 0.10
0.66 ± 0.06
0.57 ± 0.12
<0.001
0.002
<0.001
<0.001
Cup volume
0.11 ± 0.07
0.31 ± 0.17
0.37 ± 0.34
<0.001
<0.001
<0.001
0.285
Disc volume
0.76 ± 0.33
1.49 ± 0.32
1.39 ± 1.01
<0.001
<0.001
0.005
0.352
Rim volume
0.35 ± 0.17
0.64 ± 0.33
0.32 ± 0.23
<0.001
<0.001
0.669
0.001
Mean cup depth
0.18 ± 0.13
0.31 ± 0.15
0.36 ± 0.34
<0.001
0.001
0.005
0.486
Maximum cup depth
0.51 ± 0.29
1.43 ± 1.61
1.10 ± 1.39
0.019
0.010
0.018
0.326
Height variation contour
0.81 ± 0.71
1.25 ± 1.34
1.25 ± 1.35
0.234
0.281
0.101
0.994
Cirrus OCT RNFL and optic nerve head analysis
Rim area
1.20 ± 0.28
1.14 ± 0.22
0.868 ± 0.33
<0.001
0.136
<0.001
<0.001
Disc area
1.92 ± 0.40
2.51 ± 0.42
2.26 ± 0.56
<0.001
<0.001
0.008
0.009
Average C/D ratio
0.54 ± 0.14
0.71 ± 0.06
0.74 ± 0.14
<0.001
<0.001
<0.001
0.277
Vertical C/D ratio
0.50 ± 0.13
0.68 ± 0.05
0.72 ± 0.14
<0.001
<0.001
<0.001
0.050
Cup volume
0.20 ± 0.12
0.53 ± 0.23
0.55 ± 0.34
<0.001
<0.001
<0.001
0.646
Average RNFL thickness
95.33 ± 8.61
91.60 ± 9.56
76.48 ± 16.30
<0.001
0.167
<0.001
<0.001
Statistical significance was tested by ANOVA. OCT: optical coherence tomography. C/D ratio: cup/disc ratio. RNFL: retinal nerve fiber layer.
