An Updated Meta-Analysis: Risk Conferred by Glutathione S-Transferases (GSTM1 and GSTT1) Polymorphisms to Age-Related Cataract

Table 1

Characteristics of studies included in the meta-analysis.

First author	Year	Ethnicity (country)	Sample size		Number of null genotypes		References	Quality score
			Cases	Controls	Cases	Controls
GSTM1:
Pi	1996	Asian (China)	59	112	41	57	[18]	18
Hao	1999	Asian (China)	77	76	41	35	[19]	17
Xu	2007	Asian (China)	120	118	81	60	[20]	19
Zhou	2010	Asian (China)	279	145	171	95	[21]	29
Jiang	2012	Asian (China)	422	312	176	173	[22]	31
Sekine	1995	Asian (Japan)	138	62	101	30	[23]	20
Sireesha	2012	Caucasian (India)	455	205	177	94	[24]	32
Alberti	1996	Caucasian (Italy)	202	98	99	49	[25]	23
Juronen	2000	Caucasian (Estonia)	503	202	240	111	[26]	25
Saadat	2004	Caucasian (Iran)	150	150	90	58	[27]	25
Saadat	2006	Caucasian (Iran)	95	95	56	36	[28]	23
Güven	2007	Caucasian (Turkey)	195	136	105	58	[29]	29
Abdel Azeem	2009	Caucasian (Egypt)	53	73	23	46	[30]	22
Saadat	2012	Caucasian (Iran)	186	195	104	89	[31]	26
Chandra	2014	Caucasian (India)	131	126	43	68	[32]	25
GSTT1:
Zhou	2010	Asian (China)	279	145	146	60	[21]	29
Jiang	2012	Asian (China)	422	312	221	138	[22]	31
Sireesha	2012	Caucasian (India)	455	205	123	40	[24]	32
Juronen	2000	Caucasian (Estonia)	503	202	73	36	[26]	25
Saadat	2004	Caucasian (Iran)	150	150	49	46	[27]	25
Güven	2007	Caucasian (Turkey)	195	136	29	22	[29]	29
Abdel Azeem	2009	Caucasian (Egypt)	53	73	16	21	[30]	22
Saadat	2012	Caucasian (Iran)	186	195	49	57	[31]	26
Chandra	2014	Caucasian (India)	131	126	18	5	[32]	25

GSTM1: glutathione S-transferase M1; GSTT1: glutathione S-transferase T1.