Research Article

Correlative Microscopy of Lamellar Hole-Associated Epiretinal Proliferation

Table 1

Analysis of spectral-domain optical coherence tomography (SD-OCT) and immunocytochemistry of lamellar hole-associated proliferation (LHEP) removed from eyes with lamellar macular holes (LMH).

ID numberSD-OCT analysisImmunocytochemistry
LHEPERMPreop defect of ellipsoid zonePreop defect of ELMPostop defect of ellipsoid zonePostop defect of ELMAnti-GFAPAnti-CD45Anti-CD64Anti-α-SMAAnticollagen type IAnticollagen type II

1+++++++(+)(+)+
2+++++++++++
3 +++++++(+)(+)+
4 ++++++(+)+
5 +++(+)++(+)
6++++++(+)(+)++
7+++++++++++
8++++++++(+)
9+++++(+)++
10++++++(+)++

ERM: epiretinal membrane; extrafoveal location with contractive properties; ELM: external limiting membrane; GFAP: glial fibrillary acidic protein; α-SMA: α-smooth muscle actin.