Table 3: Sensitivity analyses.

Risk periods
hospitalisations
Person-yearsAdjusted rate per 10 years (95% CI)IRR (95% CI)

Exposed patients only (adjusting for age, calendar year, and other conditionsa)
Unexposed16111121.45 (1.20–1.75)1.00 (1.00-1.00)
Before 1–30 days2220.86 (0.21–3.46)0.59 (0.15–2.41)
After 1–30 days251272.02 (1.32–3.10)1.40 (0.86–2.26)
After 31–180 days582342.78 (2.02–3.81)1.91 (1.28–2.85)
After 180 days171211.75 (0.98–3.13)1.21 (0.63–2.30)
Washout4630.62 (0.23–1.69)0.43 (0.16–1.19)

Including unexposed patients (adjusting for age and calendar year)
Unexposed6267367911.39 (1.33–1.46)1.00 (1.00-1.00)
Before 1–30 days2220.74 (0.18–3.00)0.53 (0.13–2.16)
After 1–30 days251271.77 (1.11–2.82)1.27 (0.80–2.02)
After 31–180 days582342.47 (1.70–3.59)1.77 (1.22–2.58)
After 180 days171211.58 (0.85–2.93)1.13 (0.61–2.10)
Washout4630.54 (0.20–1.48)0.39 (0.14–1.06)

Exposed patients only who were dispended at least one oral beta-blocker (adjusting for age and calendar year)
Unexposed976901.43 (1.11–1.86)1.00 (1.00-1.00)
Before 1–30 days2131.36 (0.34–5.46)0.95 (0.23–3.88)
After 1–30 days12811.54 (0.85–2.80)1.08 (0.55–2.09)
After 31–180 days401552.95 (2.03–4.31)2.06 (1.26–3.36)
After 180 days12762.10 (1.06–4.15)1.46 (0.68–3.15)
Washout3390.77 (0.24–2.43)0.54 (0.16–1.75)

Exposed patients only who were not dispended oral beta-blockers (adjusting for age and calendar year)
Unexposed644221.51 (1.11–2.05)1.00 (1.00-1.00)
Before 1–30 days0880.95 (0.23–3.88)
After 1–30 days13463.04 (1.61–5.73)2.01 (0.99–4.08)
After 31–180 days18792.65 (1.46–4.80)1.76 (0.88–3.50)
After 180 days5451.18 (0.39–3.55)0.78 (0.24–2.55)
Washout1240.42 (0.06–3.05)0.28 (0.04–2.06)

CI: confidence interval; IRR: incidence rate ratio.
aOral beta-blockers (ATC code C07), calcium-channel blockers (ATC code C08), digitalis glycosides (ATC code C01AA), and antiarrhythmics (ATC code C01B).