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Journal of Ophthalmology
Volume 2015, Article ID 594615, 7 pages
Review Article

Steroids in Central Retinal Vein Occlusion: Is There a Role in Current Treatment Practice?

Ophthalmology Department, Faculty of Medicine, Khartoum Square, El Azarita, Alexandria, Egypt

Received 11 August 2015; Accepted 20 September 2015

Academic Editor: David J. Calkins

Copyright © 2015 Mohammed Ashraf and Ahmed A. R. Souka. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


With the current widespread use of anti-VEGFs in the treatment of central retinal vein occlusion (CRVO), the role for steroids has become greatly diminished. Recent large scale randomized control trials (RCTs) have established the efficacy and safety of anti-VEGFs in the treatment of CRVO. Steroids are known to cause elevations in intraocular pressure as well as increase the risk of cataract formation. With that in mind many ophthalmologists are injecting steroids less frequently. This paper aims to review some of the data pertaining to the use of steroids either as a first line monotherapy, adjunct therapy, or an alternative therapy to help answer the question: Is there currently any role for steroids in the management of CRVO?