Suppression of In Vivo Neovascularization by the Loss of TRPV1 in Mouse Cornea

Figure 3

Neovascularization in corneal stroma in histology and evaluation of its length. (a) CD31 immunostaining was performed in cryosections of the mouse cornea. In WT mouse corneas, formation of CD31-labeled neovascularization (arrows) from the limbal vessels (arrowheads) in the corneal stroma was detected in the peripheral cornea at days 3 and 7. The length of the neovascularization was less in KO mice as compared with WT mice at day 3 and day 7 (b). < 0.05; n.s.: not significant. Bar, 100 μm.

(a)

(b)