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Journal of Ophthalmology
Volume 2015 (2015), Article ID 720109, 9 pages
http://dx.doi.org/10.1155/2015/720109
Clinical Study

Prospective Randomized Study Comparing Combined Phaco-ExPress and Phacotrabeculectomy in Open Angle Glaucoma Treatment: 12-Month Follow-Up

1Department of Ophthalmology, Medical University of Białystok, M. Skłodowskiej-Curie 24A Street, 15-276 Białystok, Poland
2Department of Ophthalmology, Military Institute of Medicine, Szaserów 128 Street, 04-141 Warsaw, Poland

Received 11 March 2015; Revised 17 May 2015; Accepted 27 May 2015

Academic Editor: Kin Sheng Lim

Copyright © 2015 Joanna Konopińska et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose of the Study. To compare the efficacy and safety of phacotrabeculectomy (P-Trab) and phacoemulsification with the ExPress (P-ExPress) mini glaucoma shunt implantation. Study Plan. Prospective randomized study. Material and Methods. 85 eyes with cataract and unregulated open angle glaucoma. There were 46 eyes in the P-ExPress and 39 the P-Trab group. Intraocular pressure (IOP), the number of antiglaucoma medications, qualified and complete surgical success (defined as IOP ≤ 18.0 mmHg), visual acuity (CDVA), the number of endothelial cells, and postoperative complications and additional procedures were assessed. Results. After 12 months of observation, the average IOP in the P-Express group went from 26.4 ± 9.3 down to 17.1 ± 5 mmHg () and from 27.9 ± 12.9 down to 15.9 ± 2.7 mmHg in the P-Trab group (). No significant differences in the amount of medications used after surgery and CDVA were discovered between the groups. In the P-ExPress group, greater loss of endothelial cells was noted , compared to the P-Trab group. Conclusions. Both P-ExPress and P-Trab have comparable efficacy and similar early postoperative complication profile. The presence of additional implant (as is the case of the ExPress mini glaucoma shunt implantation) may cause progressive loss of endothelial cells.