Review Article

Immediate Sequential Bilateral Cataract Surgery: A Systematic Review and Meta-Analysis

Table 1

Characteristics of included studies.

Study IDMethodsParticipantsInterventionsOutcomesNotes

Lundström et al. 2006 [23]RCTFrom Blekinge Hospital, Karlskrona, Sweden
Inclusion: age-related cataract
Group 1: , mean age 72.5, 54.0% women, median VA 0.6/0.6 (right/left eye) prior to surgery
Group 2: , mean age 72.5, 54.3% women, median VA 0.6/0.6 (right/left eye) prior to surgery
Excluded after randomization: 6% in Group 1 and 10.9% in Group 2
No lost to follow-up: not reported
Group 1: ISBCS
Group 2: sequential bilateral cataract surgery delayed by 2 months
All had phacoemulsification
VA was 0.8 or better in 91.5% of patients in Group 1 and 91.3% of patients in Group 2. Two months after surgery total disability score (Catquest score): 7.0 in Group 1 and 7.0 in Group 2.The study was supported by the County Council of Blekinge. No conflict of interests is noted.

Sarikkola et al. 2011 [25]RCTFrom Helsinki University Eye Hospital, Helsinki, Finland
Inclusion: age-related
Group 1: mean (SD) age 75.3 (7.9), 73.6% women, preop CDVA (median) 20/60
Group 2: mean (SD) age 75.0 (8.1), 74.3% women, preop CDVA (median) 20/60
Excluded after randomization: 4% in Group 1 and 2.7% in Group 2
No lost to follow-up: 3.2% in total
Group 1: ISBCS
Group 2: delayed sequential bilateral cataract surgery
All had phacoemulsification
Postop VF-7: 24.3 (21.0) in Group 1 and 23.8 (19.2) in Group 2. Any complication (intraoperative up to 1 month postop): 106/493 in Group 1 and 124/506 in Group 2. Serious complications: 9/493 in Group 1 and 9/506 in Group 2. CDVA: 20/25 or better in 376/493 in Group 1 and 336/506 in Group 2.The study was supported by private and public research grants. No conflict of interests was reported.

Serrano-Aguilar et al. 2012 [24]RCTFrom several clinics on the Canary Islands, Spain
Inclusion: age-related cataract
Group 1: mean (SD) age 72.9 (8.2), 61.2% women, preop CDVA (median) 20/100
Group 2: mean (SD) age 71.7 (7.9), 60.5% women, preop CDVA (median) 20/100
Excluded after randomization: 5.0% in Group 1 and 3.7% in Group 2
No lost to follow-up: 0 patients
Group 1: ISBCS
Group 2: delayed sequential bilateral cataract surgery
All had phacoemulsification
Postop VA was reported as median. Any complication (intraoperative and postop + dry eyes): 39/834 in Group 1 and 59/780 in Group 2. Serious complications: 10/834 in Group 1 versus 3/780 in Group 2. VF-14: 93.3 (12.8) in Group 1 and 95.8 (8.5) in Group 2 one month after surgery on the last eye.The study was supported by public research grants.

CDVA: corrected distance visual acuity. ISBCS: immediate sequential bilateral cataract surgery. No: number. Postop: postoperative. SD: standard deviation. VA: visual acuity. VF-7: visual function questionnaire 7. VF-14: visual function questionnaire 14.