Comparative Analysis of Anterior Segment Parameters in Normal and Keratoconus Eyes Generated by Scheimpflug Tomography

Table 2

ROC curve analysis for the keratoconus eyes versus normal eyes.

Parameters	AUC	SE	95% CI		Cutoff	Sensitivity	Specificity
Topographic map
Kflat (Ant.)	0.755	0.014	0.728–0.783	<0.001	45.15	0.500	0.915
Ksteep (Ant.)	0.857	0.011	0.836–0.878	<0.001	46.45	0.685	0.929
Kmean (Ant.)	0.820	0.012	0.796–0.844	<0.001	45.25	0.646	0.863
Kmax
Astigmatism (Ant.)	0.815	0.013	0.791–0.840	<0.001	1.65	0.733	0.816
Asphericity (Ant.)	0.795	0.014	0.768–0.721	<0.001	−0.565	0.974	0.618
Kflat (Post.)	0.757	0.014	0.729–0.785	<0.001	−6.55	0.939	0.516
Ksteep (Post.)	0.842	0.012	0.819–0.865	<0.001	−6.85	0.941	0.674
Kmean (Post.)	0.819	0.012	0.795–8.44	<0.001	−6.65	0.945	0.631
Kmax	0.928	0.008	0.914–0.943	<0.001	47.05	0.839	0.935
Astigmatism (Post.)	0.802	0.013	0.776–0.828	<0.001	0.45	0.708	0.828
Asphericity (Post.)	0.780	0.014	0.752–0.807	<0.001	−0.555	0.892	0.678
TCT	0.915	0.08	0.899–0.932	<0.001	506.5	0.890	0.832
Cornea Vol	0.713	0.015	0.701–0.760	<0.001	58.55	0.695	0.687
AC Vol	0.650	0.017	0.617–0.683	<0.001	169.5	0.769	0.452
ACD	0.724	0.015	0.695–0.754	<0.001	3.155	0.703	0.631
AC Angle	0.584	0.017	0.550–0.618	<0.001	33.25	0.854	0.278
Topometric map
ISV	0.954	0.006	0.942–0.966	<0.001	31.5	0.878	0.962
IVA	0.963	0.006	0.952–0.974	<0.001	0.255	0.913	0.964
KI	0.970	0.005	0.960–0.979	<0.001	1.055	0.910	0.982
CKI	0.824	0.013	0.798–0.849	<0.001	1.015	0.727	0.982
IHA	0.883	0.10	0.863–0.902	<0.001	8.65	0.757	0.886
IHD	0.951	0.006	0.938–0.963	<0.001	0.0175	0.900	0.890
Rmin	0.929	0.008	0.914–0.943	<0.001	7.085	0.968	0.807
HOR Q	0.811	0.13	0.895–0.837	<0.001	−0.495	0.896	0.711
VERT Q	0.719	0.015	0.689–0.750	<0.001	−0.625	0.951	0.545
BAD maps
Front diff.	0.910	0.008	0.894–0.926	<0.001	8.5	0.716	1
Back diff.	0.954	0.006	0.942–0.966	<0.001	12.5	0.873	0.961
Dist.Apex-Th	0.512	0.17	0.478–0.545	0.499	0.955	0.314	0.760
F.Ele.Th	0.959	0.006	0.947–0971	<0.001	5.5	0.913	0.974
B.Ele.Th	0.967	0.005	0.956–0.977	<0.001	13.5	0.932	0.949
ProgMin	0.935	0.008	0.921–0.950	<0.001	0.925	0.854	0.972
ProgMax	0.964	0.005	0.953–0.974	<0.001	1.675	0.888	0.978
ProgAvg	0.955	0.006	0.943–0.968	<0.001	1.185	0.914	0.951
ARTmax	0.961	0.006	0.949–0.972	<0.001	311	0.966	0.907
Df	0.949	0.006	0.937–0.962	<0.001	2.575	0.847	0.972
Db	0.957	0.006	0.946–0.968	<0.001	1.72	0.882	0.943
Dp	0.954	0.006	0.942–0.967	<0.001	1.855	0.919	0.951
Dt	0.914	0.008	0.897–0.930	<0.001	0.955	0.830	0.888
Da	0.964	0.006	0.953–0.975	<0.001	1.62	0.905	0.968
D	0.972	0.005	0.963–0.982	<0.001	2.615	0.932	0.990

AUC: Area Under ROC Curve.
SE: Standard error.
CI: Confidence Interval.
: Probability.