Clinical Study

Intraocular Lens Opacification following Intracameral Injection of Recombinant Tissue Plasminogen Activator to Treat Inflammatory Membranes after Cataract Surgery

Table 1

Characteristics of patients with IOL opacification following intracameral rtPA treatment after uncomplicated cataract surgery.

CaseEyeOcular comorbidityAdditional proceduresIOL typePresenting
BCVA
Time from
surgery to rtPA
rtPA dose (μg)Time of IOL
opacification
after rtPA
After rtPA BCVAIOL
exchange
Final BCVA

1OSC-flex 570C0.001 week253 months0.00Yes0.00
2ODC-flex 570C0.404 weeks254 months0.00Yes0.30
3ODSuperflex 620H0.102 weeks258 months0.30Yes0.10
4OSPhacomorphic glaucomaC-flex 570C0.802 weeks106 weeks0.90Declined0.60
5ODTreated PDR, previous
vitrectomy and delamination
Superflex 620H0.481 week2017 months0.30Declined0.60
6ODTreated PDR, persistent DMOCombined with IVTAC-flex 570C1.002 weeks504 weeks0.78Unsuitable2.00
7OSPDR, vitreous haemorrhageCombined with PPV,
delamination and laser
Superflex 620H1.001 week4012 months0.40Declined0.50

PDR: proliferative diabetic retinopathy, DMO: diabetic macular oedema, IOL: intraocular lens, BCVA: best corrected visual acuity (measured in logMAR), and μg: microgram.