Intraocular Lens Opacification following Intracameral Injection of Recombinant Tissue Plasminogen Activator to Treat Inflammatory Membranes after Cataract Surgery
Table 1
Characteristics of patients with IOL opacification following intracameral rtPA treatment after uncomplicated cataract surgery.
Case
Eye
Ocular comorbidity
Additional procedures
IOL type
Presenting BCVA
Time from surgery to rtPA
rtPA dose (μg)
Time of IOL opacification after rtPA
After rtPA BCVA
IOL exchange
Final BCVA
1
OS
—
—
C-flex 570C
0.00
1 week
25
3 months
0.00
Yes
0.00
2
OD
—
—
C-flex 570C
0.40
4 weeks
25
4 months
0.00
Yes
0.30
3
OD
—
—
Superflex 620H
0.10
2 weeks
25
8 months
0.30
Yes
0.10
4
OS
Phacomorphic glaucoma
—
C-flex 570C
0.80
2 weeks
10
6 weeks
0.90
Declined
0.60
5
OD
Treated PDR, previous vitrectomy and delamination
—
Superflex 620H
0.48
1 week
20
17 months
0.30
Declined
0.60
6
OD
Treated PDR, persistent DMO
Combined with IVTA
C-flex 570C
1.00
2 weeks
50
4 weeks
0.78
Unsuitable
2.00
7
OS
PDR, vitreous haemorrhage
Combined with PPV, delamination and laser
Superflex 620H
1.00
1 week
40
12 months
0.40
Declined
0.50
PDR: proliferative diabetic retinopathy, DMO: diabetic macular oedema, IOL: intraocular lens, BCVA: best corrected visual acuity (measured in logMAR), and μg: microgram.