To Study and Determine the Role of Anterior Segment Optical Coherence Tomography and Ultrasound Biomicroscopy in Corneal and Conjunctival Tumors

Table 3

Articles describing the use of UBM and AS-OCT in conjunctival and corneal tumors.

Author, year	Study	Number of patients	Imaging technique	Aim	Tumor type	Results	Conclusion
UBM versus AS-OCT
Buchwald et al., 2003	Optical coherence tomography versus ultrasound biomicroscopy of conjunctival and eyelid lesions—prospective study	38 tumors of 35 patients	UBM (30 MHz) and AS-OCT (1310 nm)	To compare the value of UBM and AS-OCT in the diagnosis of conjunctival and eyelid lesions	13 conjunctival lesions and 25 eyelid lesions: pterygium (8/38), seborrheic keratosis (7/38), cyst of the eyelid (5/38), basal cell carcinoma of the eyelid (4/38), compound nevus of the conjunctiva (4/38), chalazion (3/38), primary acquired melanosis (1/38), actinic keratosis (1/38), nevus (1/38), cavernous haemangioma (1/38), melanoma in situ (1/38), foreign body (1/38), epidermoid cyst (1/38)	AS-OCT; (i) More reliable imaging: small cystic structures of compound nevus; (ii) Assessment of the margins of the tumors (particularly in depth) was impossible or uncertain; AS-OCT and UBM; Solid tumors: the definite diagnosis could not be differentiated by UBM or OCT alone	OCT; Show very small cystic structures more distinctly than UBM; UBM; Better for assessing the margins of the tumor than OCT
Bianciotto et al., 2011	Assessment of anterior segment tumors with ultrasound biomicroscopy versus anterior segment optical coherence tomography in 200 cases—retrospective, noninterventional case series	200	UBM (50 MHz probe) and AS-OCT (1310 nm)	To compare UBM versus AS-OCT for imaging of tumors of the anterior segment of the eye	6 conjunctival lesions (diagnosis not mentioned), 0 corneal lesions, 194 other locations: nevus (75/200), melanoma (47/200), cyst (48/200), epithelioma (adenoma) (5/200), metastasis (4/200), melanocytosis (4/200) and melanocytoma (4/200), others (3/200)	UBM; (i) Better overall tumor visualization (138 [69%] versus 62 [31%]); (ii) Better resolution of the posterior margin (147 [74%] versus 53 [27%]); (iii) Better resolution for pigmented tumors (; 107 [66%] versus 55 [34%]); (iv) Better resolution for nonpigmented tumors (; 23 [61%] versus 15 [39%]); AS-OCT; (i) Better resolution of the anterior margin (40 [20%] versus 160 [80%]); (ii) Better overall resolution of anterior segment anatomy (41 [21%] versus 159 [80%])	UBM > AS-OCT; (i) Anterior segment tumors: better visualization of the posterior margin and overall better images for entire tumor configuration