Prognostic Factor Analysis of Intraocular Pressure with Neovascular Glaucoma

Table 3

Prognostic factors influencing final IOP in patients with NVG (multivariate statistics). Log-rank test and Cox proportional-hazards models were created to identify prognostic factors of NVG using final IOP > 21 mmHg as the study end-point. Angle-closure was associated with a 3-fold worsening in NVG-IOP prognosis. Patients with NVG with PDR had relatively better prognosis than those with NVG induced by other causes.

Covariates	Hazard ratio	95% confidence interval	Log-rank test; )
Angle-closure NVG group	3.059	1.898–4.916	0.0002
Causative disease, PDR	0.759	0.391–0.930	0.0002
Treatments, LEC	0.412	0.251–0.667	0.0809
Causative disease, RVO	—	—	0.0123
Causative disease, OIS	—	—	0.0384
Previous treatments, PRP	—	—	0.1667
Previous treatments, PPV	—	—	0.2717
Pre-existing complications, hyphema	—	—	0.3930
Pre-existing complications, VH	—	—	0.8108
Treatments, anti-VEGF therapy	—	—	0.3128
Treatments, additional PRP	—	—	0.3642
Treatments, PPV	—	—	0.9287

NVG, neovascular glaucoma; PDR, proliferative diabetic retinopathy; LEC, trabeculectomy with mitomycin C; RVO, retinal vein occlusion; OIS, ocular ischemic syndrome; PRP, panretinal laser photocoagulation; PPV, pars plana vitrectomy; VH, vitreous hemorrhage.