Changes of Corneal Wavefront Aberrations in Dry Eye Patients after Treatment with Artificial Lubricant Drops

Table 1

Clinical data analysis for the dry eye patients at baseline and two weeks after treatment.

	Treatment group ()			Control group ()
	Baseline	Two weeks		Baseline	Two weeks
Age (year)	31.03 ± 4.73 (23–39)		—	29.00 ± 5.30 (21–38)		—	>0.05
Male/female	14/16		—	12/10		—	>0.05
BCVA (LogMAR)	0.14 ± 0.09	0.10 ± 0.05	0.03	0.12 ± 0.09	0.11 ± 0.07	>0.05	>0.05
SE (diopter)^#	−1.59 ± 1.16 (−6.25–+ 0.50)		—	−1.31 ± 1.56 (−5.75–+1.00)		—	>0.05
TBUT (s)	4.93 ± 1.31	6.27 ± 1.20	<0.01	4.95 ± 1.13	5.18 ± 1.05	>0.05	<0.01
Schirmer I score (mm)	11.80 ± 1.77	12.10 ± 1.42	>0.05	11.14 ± 1.73	11.36 ± 1.56	>0.05	>0.05
Fluorescein stain positive (eye)	18 (60%)	5 (16.7%)	<0.01	12 (54.55%)	13 (57%)	>0.05	<0.01
Eye dryness /burn/foreign body sensation (eye)	25 (83.3%)	11 (36.7%)	<0.01	18 (81.8%)	19 (86.4%)	>0.05	<0.01
Vision disturbance (blur/discomfort/night vision) (eye)	21 (70%)	9 (30%)	<0.01	15 (68.2%)	16 (72.8%)	>0.05	<0.01

^#SE denotes spherical equivalence, which was calculated as sphere diopters plus half-cylinder diopters. SE of the right eyes for each subject was used for analysis.
The numbers for these tests denote the number of eyes showing positive results and the percentage in parenthesis denotes the rate of positive results.
indicates the significant level of -test within treatment or control groups between baseline and two weeks after treatment.
indicates the significant level of -test between treatment and control groups after two weeks.