Clinical Study
A Combination of Intrastromal and Intracameral Injections of Amphotericin B in the Treatment of Severe Fungal Keratitis
Table 1
Clinical data of patients with severe fungal keratitis treated with combined intrastromal and intracameral amphotericin B.
| Case number | Age (years)/gender | Risk factor for fungal keratitis | History | Duration of onset of symptoms (days) | Initial BCVA | Size of ulcer (mm) | Fungal identification | Repeated injection | Final BCVA | Healed with |
| 1 | 37/F | Corneal trauma | Diabetes | 27 | CF | 5 × 6 | Fusarium | 1 Isi | 20/40 | Leucoma | 2 | 56/M | Unknown | Steroid | 17 | HM | 5.5 6.5 | Not identified | 2 Ici | 20/200 | Leucoma | 3 | 67/M | Corneal trauma | Diabetes | 35 | LP | 6 7 | Alternaria | 1 Iii | CF | Leucoma | 4 | 71/M | Unknown | No | 33 | HM | 6 6 | Fusarium | — | CF | Leucoma | 5 | 57/F | Corneal trauma | Steroid | 39 | HM | 7 8 | Aspergillus | 2 Isi + 1 Isi | HM | Adherent leucoma | 6 | 63/F | Contact lens | Diabetes | 46 | LP | 6 7 | Negative | — | 20/300 | Leucoma | 7 | 56/M | Corneal trauma | Steroid | 63 | LP | 5 7 | Aspergillus | 2 Ici | HM | Adherent leucoma | 8 | 47/M | Unknown | No | 52 | HM | 5.5 6.5 | Fusarium | — | CF | Leucoma | 9 | 43/M | Corneal trauma | Steroid | 41 | CF | 6 8 | Negative | — | 20/200 | Leucoma |
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CF, counting fingers; F, female; HM, hand movements; Iii, combined intrastromal and intracameral injections; Isi, intrastromal injections; Ici, intracameral injections; LP, light perception; M, male.
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