Outcomes of Infectious versus Sterile Perforated Corneal Ulcers after Therapeutic Penetrating Keratoplasty in the United States

Table 1

Underlying ulcer pathologies that led to corneal perforation requiring therapeutic penetrating keratoplasty.

Corneal ulcer type	Preoperative diagnosis
Sterile ()	Peripheral ulcerative keratitis due to an underlying autoimmune condition
	Associated with rheumatoid arthritis ()
	Associated with systemic lupus erythematosus ()
	Underlying neurotrophic keratopathy
	Associated with previous herpes zoster keratoconjunctivitis ()
	Associated with diabetic neuropathy ()
	Associated with nerve palsy after brain neoplasm excision ()
	Associated with dry eye syndrome and other chronic ocular surface disease ()
	Acquired limbal stem cell deficiency due to previous external beam
	Radiation to periocular skin neoplasm ()
	Graft versus host disease after bone marrow transplantation ()
	Stevens Johnson syndrome ()
	Toxicity of topical nonsteroidal anti-inflammatory drug ()
	Traumatic alkaline chemical injury ()
Infectious ()	Bacterial keratitis
	Associated with contact lens wear ()
	Occurring after previous corneal transplantation ()
	Associated with other chronic ocular surface diseases ()
	Fungal keratitis
	Associated with contact lens wear ()
	Occurring after previous corneal transplantation ()
	Associated with other chronic ocular surface diseases ()