Rotating Scheimpflug Imaging Indices in Different Grades of Keratoconus
Table 3
The indices with highest AUROC.
Indices
AUROC
95% CI
Criterion
Sensitivity
Specificity
LR+
LR−
AUROC compared to that of PPI-Max
PPI-Max
0.987
0.958 to 0.998
>1.4
91.78
98.06
47.27
0.084
ART-Max
0.987
0.957 to 0.998
≤412
97.26
93.2
14.31
0.029
= 0.880
Elevation of the thinnest point from the 9 mm anterior BFS
0.979
0.945 to 0.995
>7
95.89
92.23
12.35
0.045
= 0.501
Elevation of the thinnest point from the 8 mm anterior BFS
0.968
0.930 to 0.989
>5
91.78
96.12
23.63
0.086
= 0.288
Elevation of the thinnest point from the 8 mm posterior BFS
0.979
0.945 to 0.995
>20
86.3
100
N/A
0.14
= 0.229
Elevation of the thinnest point from the 7 mm posterior BFS
0.971
0.934 to 0.990
>10
87.67
100
N/A
0.12
= 0.217
Elevation of the thinnest point from the 9 mm posterior BFS
0.977
0.942 to 0.994
>22
89.04
96.12
22.93
0.11
= 0.199
PPI-Avg
0.978
0.944 to 0.994
>1.1
87.67
98.06
45.15
0.13
= 0.147
Elevation of the thinnest point from the 7 mm posterior BFTE
0.953
0.910 to 0.979
>10
87.67
99.03
90.3
0.12
= 0.104
ART-Avg
0.976
0.942 to 0.993
≤496
94.52
94.17
16.23
0.058
= 0.089
All other tested indices
< 0.05
AUROC: area under the receiver operating characteristic curve. 95% CI: 95% confidence interval of the AUROC. LR+: likelihood ratio of positive results. LR−: likelihood ratio of negative results. from PPI-Max: probability of chance that the AUROC is less than that of PPI-Max. PPI-Max: Pachymetry Progression Index-Maximum, ART-Max: Ambrósio’s Relational Thickness-Maximum, BFS: best-fit sphere, PPI-Avg: Pachymetry Progression Index-Average, BFTE: best-fit toric ellipsoid, and ART-Avg: Ambrósio’s Relational Thickness-Average.
