Clinical Study

Retinal Detachment in Down Syndrome: Characteristics and Surgical Outcomes

Table 2

Summary of the result.

Number of eyes18
Mean age11.3 years (range, 4 to 26 years)
Eye
 Right8
 Left10
 Both3
Lens status
 Clear2 (11.1%)
 Cataractous9 (50%)
 Pseudophakia4 (22.2%)
 Aphakia3 (16.6%)
Type of retinal breaks8 eyes with HST3 eyes with GRT8 eyes with atrophic or operculated holes1 eye with retinal dialysis1 eye with unidentifiable break
MaculaAll eyes with macula off detachment
Quadrant of retinal detachment Total in 15 (83.3%) eyes3 quadrants in 2 (11.1%) eyes2 quadrants in one (5.5%) eye
PVR grade
 Grade B2 (11.1%)
 Grade C6 (33.3%)
  Anterior2
  Posterior1
  Anterior and posterior2
  Undetermined1
SurgerySB in 6 (33.3%) eyesPPV in 1 (5.5%) eyePPV + SB in 11 (61.1%) eyes
PPLIn 5 (27.8%) eyes
First subsequent surgeryPPV in 3 (16.7%) eyesPPV + SB in 1 (5.5%) eyeSO removal in 1 (5.5%) eyesPhaco + PC IOL/SO removal in 1 (5.5%) eye
Second subsequent surgerySecondary IOL and SO removal in 1 (5.5%) eyeSB removal and intravitreal AB in 1 (5.5%) eye
Buckle detailsBand + tire in 5 (27.7%) eyesBand in 12 (66.7%) eyes
Preoperative BCVAFrom following light to counting fingers (median: following and fixation) (10/18 eyes)
Postoperative BCVAFrom light perception to 20/125 (median: hand motion) (11/18 eyes)
Anatomical resultsFlat in 88.8% (16 eyes)Detached in 11.2% (2 eyes)
Follow-upRanged from 3.1 to 210.5 months (mean, 48.0 months)

HST: horseshoe tear; GRT: giant retinal tear; PPV: pars plana vitrectomy; SB: scleral buckle; PPL: pars plana lensectomy; PC IOL: posterior chamber intraocular lens; IOL: intraocular lens; AB: antibiotic; PVR: proliferative vitreoretinopathy.