Choroidal Thickness in Patients with Mild Cognitive Impairment and Alzheimer’s Type Dementia
Table 2
Relationship of choroidal thickness with Alzheimer’s type dementia (ATD) and mild cognitive impairment (MCI).
Choroidal thickness (μm)
ATD ()
MCI ()
Controls ()
value
ATD versus controls
MCI versus controls
ATD versus MCI
Mean thickness (SD)
Mean thickness (SD)
Mean thickness (SD)
Mean difference (SE)
† value
Mean difference (SE)
† value
Mean difference (SE)
† value
Subfoveal
215.6 ± 64.5
228.7 ± 52.9
272.7 ± 60.1
<0.001
−57.1 (9.4)
<0.001
−44.0 (9.6)
<0.001
−13.1 (9.9)
0.187
Temporal 0.5 mm
200.4 ± 60.0
211.0 ± 49.9
250.2 ± 55.3
<0.001
−49.7 (8.7)
<0.001
−39.2 (8.9)
<0.001
−10.5 (9.2)
0.253
Nasal 0.5 mm
194.9 ± 63.4
204.7 ± 53.6
244.2 ± 60.5
<0.001
−49.3 (9.4)
<0.001
−39.5 (9.6)
<0.001
−9.7 (9.8)
0.324
Temporal 1.5 mm
192.5 ± 59.3
198.3 ± 47.9
239.0 ± 53.4
<0.001
−46.5 (8.5)
<0.001
−40.7 (8.6)
<0.001
−5.7 (8.9)
0.519
Nasal 1.5 mm
171.3 ± 64.3
182.7 ± 59.7
216.6 ± 68.4
<0.001
−45.3 (10.2)
<0.001
−33.9 (10.4)
0.001
−11.3 (10.7)
0.289
Temporal 3 mm
172.1 ± 50.1
174.4 ± 48.0
210.2 ± 43.9
<0.001
−38.1 (7.4)
<0.001
−35.8 (7.6)
<0.001
−2.2 (7.8)
0.772
Nasal 3 mm
116.5 ± 39.2
120.0 ± 48.3
141.7 ± 52.8
0.002
−21.7 (7.5)
0.004
−25.2 (7.6)
0.001
3.5 (7.9)
0.657
SD: standard deviation, SE: standard error, value represents comparison among three groups, and † value represents the pairwise comparison between two groups. ANOVA. Post hoc Bonferroni test.
