Clinical Study

Effectiveness and Optical Quality of Topical 3.0% Diquafosol versus 0.05% Cyclosporine A in Dry Eye Patients following Cataract Surgery

Table 1

Baseline characteristics in the diquafosol and cyclosporin group.

Diquafosol
()
Cyclosporin A
()

Age (yrs)64.3 ± 9.4463.4 ± 12.20.892
Gender ratio (M/F)0.670.670.750
Spherical equivalent (D)−0.75 ± 0.45−0.5 ± 0.650.368
OSDI index (0–100)20.1 ± 13.8822.29 ± 13.660.798
TBUT (s)3.17 ± 1.013.7 ± 1.080.141
Schirmer 1 test (mm/5 min)7.7 ± 3.688.4 ± 3.600.278
Oxford score (0–5)1.41 ± 0.621.5 ± 0.830.798
Total aberration (µm)1.00 ± 0.580.87 ± 0.350.684
Total HOAs (µm)0.33 ± 0.220.27 ± 0.100.752
Vertical coma (µm)0.20 ± 0.190.27 ± 0.220.357
Horizontal coma (µm)0.28 ± 0.210.32 ± 0.290.916
Vertical trefoil (µm)0.25 ± 0.190.23 ± 0.240.478
Oblique trefoil (µm)0.40 ± 0.340.29 ± 0.220.442
Spherical aberration (µm)0.20 ± 0.130.21 ± 0.140.707

D = diopter; M = male; F = female; OSDI = ocular surface disease index; TBUT = tear break-up time; HOAs = higher-order aberrations.
Mean ± standard deviation.
There was no statistically significant difference between 2 groups in baseline characteristics by Mann-Whitney test or Fisher’s exact test ().