Effectiveness and Optical Quality of Topical 3.0% Diquafosol versus 0.05% Cyclosporine A in Dry Eye Patients following Cataract Surgery
Table 1
Baseline characteristics in the diquafosol and cyclosporin group.
Diquafosol ()
Cyclosporin A ()
Age (yrs)
64.3 ± 9.44
63.4 ± 12.2
0.892
Gender ratio (M/F)
0.67
0.67
0.750
Spherical equivalent (D)
−0.75 ± 0.45
−0.5 ± 0.65
0.368
OSDI index (0–100)
20.1 ± 13.88
22.29 ± 13.66
0.798
TBUT (s)
3.17 ± 1.01
3.7 ± 1.08
0.141
Schirmer 1 test (mm/5 min)
7.7 ± 3.68
8.4 ± 3.60
0.278
Oxford score (0–5)
1.41 ± 0.62
1.5 ± 0.83
0.798
Total aberration (µm)
1.00 ± 0.58
0.87 ± 0.35
0.684
Total HOAs (µm)
0.33 ± 0.22
0.27 ± 0.10
0.752
Vertical coma (µm)
0.20 ± 0.19
0.27 ± 0.22
0.357
Horizontal coma (µm)
0.28 ± 0.21
0.32 ± 0.29
0.916
Vertical trefoil (µm)
0.25 ± 0.19
0.23 ± 0.24
0.478
Oblique trefoil (µm)
0.40 ± 0.34
0.29 ± 0.22
0.442
Spherical aberration (µm)
0.20 ± 0.13
0.21 ± 0.14
0.707
D = diopter; M = male; F = female; OSDI = ocular surface disease index; TBUT = tear break-up time; HOAs = higher-order aberrations. Mean ± standard deviation. There was no statistically significant difference between 2 groups in baseline characteristics by Mann-Whitney test or Fisher’s exact test ().