Comparison of Two Different OCT Systems: Retina Layer Segmentation and Impact on Structure-Function Analysis in Glaucoma

Table 3

Total macula and ganglion cell layer mean thickness, in micrometers (µm), among groups and p values in the central 10°.

	POAG	Controls	value	AUC
MT (mean ± SD)
Cirrus
MT	297.6 ± 13.5	307.9 ± 12.1	0.036	0.789
Spectralis
MT	319.0 ± 13.0	329.8 ± 11.7	0.027	0.801
cMT	319.0 ± 12.9	329.8 ± 11.7	0.027	0.805
GCIPL (mean ± SD)
Cirrus
GCIPL	68.5 ± 8.7	80.7 ± 4.7	<0.01	0.879
mGCIPL	61.2 ± 10.8	79.5 ± 4.7	<0.01	0.930
Spectralis
GCIPL	75.7 ± 13.8	93.3 ± 4.6	<0.01	0.886
cGCIPL	76.1 ± 13.7	93.4 ± 4.6	<0.01	0.886

MT: full macular thickness, GCIPL: ganglion cell-inner plexiform layer thickness, cMT and cGCIPL: average values after manual correction of layer segmentation in Spectralis OCT, mGCIPL: minimum GCIPL value calculated by Cirrus software. AUC: area under the ROC curve. SD: standard deviation. values were obtained with paired -test and posterior adjustment with FDR (false discovery rate).