Research Article
Effect of Hydroxychloroquine on the Retinal Layers: A Quantitative Evaluation with Spectral-Domain Optical Coherence Tomography
Table 1
Demographic characteristics and clinical data of users of hydroxychloroquine and controls.
| | | Hydroxychloroquine users | Controls | value | | Mean ± SD | Mean ± SD |
| | Subjects () | 51 | 30 | — | | Eye () | 51 | 30 | — | | Sex (male/female) | 1/50 | 1/29 | — | | Age, y | 45.0 ± 13.16 | 42.1 ± 14.3 | 0.35 | | IOP, mmHg | 15.95 ± 1.32 | 16.17 ± 1.47 | 0.18 | | Axial length, mm | 23.03 ± 0.66 | 23.03 ± 0.67 | 0.95 | | CCT, µm | 540.42 ± 32.90 | 546.28 ± 3.78 | 0.25 | | BMI, kg/m2 | 25.17 ± 4.12 | 24.64 ± 4.15 | 0.58 | | Cumulative dose, g | 648.41 ± 512.32 | NA | — | | Duration of use, mo | 55.25 ± 41.27 | NA | — | | Adjusted daily dose, mg/kg/d | 8.75 ± 0.11 | NA | — | | Diagnosis of patients, (%) | | | | | Rheumatoid arthritis | 20 (39.2) | NA | — | | Systemic lupus erythematosus | 19 (37.3) | NA | — | | Sjögren’s syndrome | 12 (23.5) | NA | — |
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IOP: intraocular pressure; CCT: central corneal thickness; BMI: body mass index; SD: standard deviation; value Student’s -test, < 0.05.
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