Clinical Features and Visual Outcomes of Optic Neuritis in Chinese Children

Table 3

Factors for visual outcomes in Chinese children with optic neuritis.

Factors		Total eyes	Final VA ≥ 20/40 (%)	value
Age at onset	Age ≤ 10 years	30	21 (70%)	0.039
	Age > 10 years	46	20 (43.5%)
Sex	Female	46	24 (52.17%)	0.701
	Male	30	17 (56.7%)
Experience	Unilateral attack	39	20 (51.3%)	0.632
	Bilateral attack	37	21 (56.8%)
Initial VA	VA > CF	42	25 (59.5%)	0.278
	VA ≤ CF	34	16 (47.1%)
Funduscopy	ODE	22	14 (63.6%)	0.501
	Normal	54	30 (55.6%)
Systemic diseases	ADEM/MS/SLE/NMOSD	18	8 (44.4%)	0.454
	ION	58	32 (55.2%)
Orbital MRI imaging	Normal	7	4 (57.1%)	0.934
	Abnormal (T2 lesions)	35	20 (58.8%)
AQP-4 IgG status	Seropositive	13	5 (38.5%)	0.374
	Seronegative	34	18 (52.9%)

VA, visual acuity; CF, count finger; ODE, optic disc edema; ION, isolated optic neuritis; ADEM, acute disseminated encephalomyelitis; MS, multiple sclerosis; SLE, systemic lupus erythematosus; AQP-4 IgG, anti-aquaporin-4 antibody IgG; and MRI, magnetic resonance imaging.