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Journal of Ophthalmology
Volume 2017, Article ID 1536030, 7 pages
https://doi.org/10.1155/2017/1536030
Research Article

Transient Peripapillary Retinoschisis in Glaucomatous Eyes

1Rotterdam Ophthalmic Institute, The Rotterdam Eye Hospital, Rotterdam, Netherlands
2Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, Netherlands

Correspondence should be addressed to Josine van der Schoot; ln.latipsoheye@toohcsrednav.j

Received 26 September 2016; Accepted 22 December 2016; Published 12 January 2017

Academic Editor: Lisa Toto

Copyright © 2017 Josine van der Schoot et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose. To investigate transient focal microcystic retinoschisis in glaucomatous eyes in images obtained with several imaging techniques used in daily glaucoma care. Methods. Images of 117 glaucoma patients and 91 healthy subjects participating in a large prospective follow-up study into glaucoma imaging were reviewed. Participants were measured with spectral domain optical coherence tomography (SD-OCT), scanning laser polarimetry (SLP), scanning laser tomography (SLT), and standard automated perimetry (SAP). The presence of a focal retinoschisis in SD-OCT was observed and correlated to SLP, SLT, and SAP measurements, both cross-sectionally and longitudinally. Results. Seven out of 117 glaucoma patients showed a transient, localised, peripapillary, heterogeneous microcystic schisis of the retinal nerve fiber layer (RNFL) and sometimes other retinal layers as well in SD-OCT. None of the healthy eyes showed this phenomenon nor did any of the other imaging techniques display it as detailed and consistently as did the SD-OCT. SAP showed a temporarily decreased focal retinal sensitivity during the retinoschisis and we found no signs of glaucomatous progression related to the retinoschisis. Conclusions. Transient microcystic retinoschisis appears to be associated with glaucomatous wedge defects in the RNFL. It was best observed with SD-OCT and it was absent in healthy eyes. We found no evidence that the retinoschisis predicted glaucomatous progression.