Assessment of Ocriplasmin Effects on the Vitreoretinal Compartment in Porcine and Human Model Systems
Uptake of ocriplasmin by retinal cells. (a) Fluorescence microscopy of Müller and RPE cells after treatment with Alexa 488 labeled ocriplasmin. (b) Dynamics of Alexa 488 ocriplasmin uptake as studied by flow cytometry. (c) Assessment of colocalization of Alexa 488 ocriplasmin with endosomal transport vehicles by confocal microscopy. Individual channels are presented in Supplemental Figure .
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