The Estimates of Retinal Ganglion Cell Counts Performed Better than Isolated Structure and Functional Tests for Glaucoma Diagnosis

Table 1

Demographic and clinical characteristics of the study participants ().

	Healthy subjects ()		Glaucoma patients ()
	Mean ± SD	Range	Mean ± SD	Range
Age (years)	58.6 ± 8.8	44.6 to 77.9	68.1 ± 11.3	44.7 to 85.6
SAP MD (dB)	−1.05 ± 1.05	−3.57 to 1.42	−7.91 ± 6.81	−30.15 to −0.71
SAP PSD (dB)	1.52 ± 0.22	1.10 to 1.98	6.56 ± 4.55	1.65 to 15.26
RNFL thickness (μm)	100.07 ± 10.01	80 to 128	73.54 ± 16.54	39 to 107
Estimated RGC count	986,396 ± 143,315	722,128 to 1,381,549	535,479 ± 204,646	34,128 to 889,775

SAP MD: standard automated perimetry mean deviation; SAP PSD: standard automated perimetry pattern standard deviation; RNFL: retinal nerve fiber layer; RGC: retinal ganglion cell. , healthy subjects versus glaucoma patients. Welch’s t-test was used to compare age, SAP MD, SAP PSD, and average RNFL thickness of unequal samples.