Author Year Postoperative complications (n , %) Reoperations (n , %) Sclemm’s canal devices Trabectome Lee et al. [38 ] 2016 Herpetic keratitis reactivation = 1 (5.3) AC washout = 1 (5.3) IOP > 21 mmHg = 5 (26.3) Repeat glaucoma surgery = 2 (10.5) Bussel et al. [37 ] 2014 Transient hypotony = 5 (6.8) Trabeculectomy = 4 (5.5) Tube surgery = 6 (8.2) Cyclophotocoagulation = 2 (2.7) Repeat Trabectome = 1 (1.4) Jordan et al. [40 ] 2013 Reflux bleeding = 512 (91.9) AC lavage = 2 (0.4) IOP > 30 mmHg = 44 (7.8) Cystoid macular edema = 3 (0.5) Maeda et al. [64 ] 2013 Reflux bleeding = 80 (100) Repeat glaucoma surgery = 13 (16.3) Reoperation (glaucoma surgery) = 13 (16.3) Ting et al. [36 ] 2012 Reflux bleeding = 692 (96.5) Repeat glaucoma surgery = 190 (23.0) Early hypotony = 5 (0.6) Francis et al. [42 ] 2008 Transient hypotony = 4 (1.3) Trabeculectomy = 7 (2.3) IOP > 10 mmHg from baseline = 32 (10.5) Tube surgery = 1 (0.3) Reflux bleeding = 238 (78.3) SLT = 1 (0.3) Minckler et al. [66 ] 2005 Reflux bleeding = 37 (100) 0 Persistent minimal DM injury = 1 (2.7) Peripheral anterior synaechiae = 9 (24.3) Goniosynechiae = 5 (13.5) IOP > 5 mmHg from baseline = 2 (5.4) Babighian et al. [49 ] 2010 IOP > 5 mmHg from baseline = 3 (20) 0 Wilmsmeyer et al. [48 ] 2006 Iris adhesion to corneal tunnel = 2 (1.5) Repeat glaucoma surgery = 25 (18.6) Fibrin reaction = 3 (2.2) CRVO = 1 (0.7) iStent Tan and Au [23 ] 2016 Transient hyphema = 1 (2.4) 0 Neuhann [22 ] 2015 Stent not visible = 1 (1.6) Cyclophotocoagulation = 3 (4.8) Posterior capsular opacification = 1 (1.6) Shunt surgery = 2 (3.2) Katz et al. [7 ] 2015 0 0 Vold et al. [15 ] 2016 Intraoperative stent malposition = 2 (3.7) 0 Transient hyphema = 1 (1.9) Intraoperative iridodialysis = 1 (1.9) Lindstrom et al. [16 ] 2016 0 0 Fea et al. [20 ] 2015 0 Donnenfeld et al. [10 ] 2015 Hyphema = 2 (5.1) AC paracentesis = 1 (2.6) Ahmed et al. [11 ] 2014 Transient hypotony = 1 (2.6) 0 Progression of cataract = 4 (10.3) Corneal ulcer = 1 (2.6) Arriola-Villalobos et al. [12 ] 2013 0 0 Craven et al. [17 ] 2012 Stent obstruction = 5 (4.3) Trabeculoplasty = 1 (0.9) Stent malposition = 3 (2.6) Stent repositioning = 3 (2.6) YAG laser for stent obstruction = 1 (0.9) Stent replacement = 1 (0.9) Focal argon laser photocoagulation = 1 (0.9) Patel et al. [26 ] 2013 Hyphema = 1 (2.3) 0 Arriola-Villalobos et al. [25 ] 2012 0 0 Buchacra et al. [9 ] 2011 Stent malposition = 1 (10.0) 0 Mild hyphema = 7 (70.0) IOP ≥ 30 mmHg = 1 (10.0) Corneal edema = 2 (20.0) Stent obstruction by blood clot = 3 (30.0) Samuelson et al. [18 ] 2011 Stent obstruction = 4 (4.0) Stent repositioning = 3 (3.0) Stent malposition = 3 (3.0) Stent replacement = 1 (1.0) Elevated IOP = 2 (2.0) Elevated IOP requiring treatment = 1 (1.0) YAG laser for stent obstruction = 1 (1.0) Fernandez-Barrientos et al. [13 ] 2010 Stent malposition = 6 of 34 stents (17.6) 0 Stent fall out = 1 of 34 stents (2.9) Spiegel et al. [27 ] 2009 Stent malposition (no repositioning) = 6 (10.3) Trabeculectomy = 2 (3.4) Stent obstruction = 7 (12.1) Stent repositioning = 1 (1.7) Argon laser = 1 (1.7) Stent replacement = 2 (3.4) Corneal paracentesis = 1 (1.7) Vandewalle et al. [24 ] 2009 Stent malposition = 1 (10.0) 0 Corneal erosion = 2 (20.0) Blood reflux into angle = 5 (50.5) Voskanyan et al. [29 ] 2014 Elevated IOP requiring medications = 10 (10.1) Trabeculectomy = 1 (1.0) YAG laser for stent obstruction = 2 (2.0) Phacotrabeculectomy = 1 (1.0) Argon laser for stent obstruction = 1 (1.0) Goniotrephenation = 1 (1.0) Stent obstruction = 3 (3.0) Deep sclerectomy = 1 (1.0) Stent malposition = 1 (1.0) Goniosynechiae (without treatment) = 1 (1.0) Lens-iris synechiae (laser treatment) = 1 (1.0) Stent not visible upon gonioscopy = 13 (13.1) Arriola-Villalobos et al. [30 ] 2016 0 0 Hydrus Fea et al. [33 ] 2016 Transient IOP spike = 2 (6.5) 0 BCVA < 2 lines from baseline = 3 (9.7) Gandolfi et al. [34 ] 2016 Transient hyphema = 4 (19.0) 0 IO ≥ 30 mmHg within 48 hrs = 1 (4.8) YAG lysis of PAS = 4 (19.0) Pfeiffer et al. [32 ] 2015 IOP > 10 mmHg from baseline = 2 (4.0) Repeat glaucoma surgery = 1 (2.1) Focal PAS = 9 (18.8) Suprachoroidal devices CyPass Vold et al. [51 ] 2016 Corneal abrasion = 7 (1.9) Secondary ocular surgical intervention = 20 (5.5) Corneal edema = 13 (3.5) Cyclodialysis cleft > 2 mm circumference = 7 (1.9) Iritis = 32 (8.6) Hypotony = 11 (29.9) IOP ≥ 10 mmHg above baseline = 16 (4.3) Cystoid macular edema = 6 (1.3) Stent obstruction = 8 (2.1) Conjunctivitis = 4 (1.0) Visual field loss progression = 25 (6.7) Garcia-Feijoo et al. [54 ] 2015 IOP > 30 mmHg = 7 (10.8) Trabeculectomy = 9 (13.8) Transient hyphema = 4 (6.2) Additional CyPass = 2 (3.1) BCVA reduced by ≥2 lines = 2 (3.1) Laser trabeculoplasty = 1 (1.6) Hoeh et al. [53 ] 2016 Early postoperative IOP elevation = 2 (1.2) Repeat glaucoma surgery = 10 (6.0) Late postoperative IOP elevation = 3 (1.8) Implant reposition = 1 (0.6) Mild transient hyphema = 2 (1.2) Implant explantation = 1 (0.6) Hypotony = 23 (13.8) Endothelial touch = 2 (1.2) Implant obstruction = 9 (5.4) Macular edema = 1 (0.6) Hoeh et al. [52 ] 2013 AC reaction > 1 month = 8 (4.4) Device repositioning = 1 (0.6) Early hypotony (<1 month) = 25 (13.8) Repeat glaucoma surgery = 9 (5.0) Hypotony > 1 month = 1 (0.5) Shallow AC without central touch = 1 (0.5) IOP > 10 mmHg from baseline = 19 (10.5) Postoperative hyphema = 2 (1.1) Subconjunctival devices XEN-45 Perez-Torregrosa et al. [55 ] 2016 Encapsulation of filtration bleb = 1 (3.3) 0 InnFocus Batlle et al. [63 ] 2016 Tube-iris touch = 3 (13.0) Repeat glaucoma surgery = 1 (4.3) Transient hypotony < 3 months = 3 (13.0) AC paracentesis = 1 (4.3) Shallow or flat AC = 3 (13.0) Hyphema = 2 (8.7) Choroidal effusion/detachment = 2 (8.7) Elevated IOP requiring bleb needling = 1 (4.3) Tube obstruction = 1 (4.3) Vitreous hemorrhage = 1 (4.3) Bleb leak = 1 (4.3)
