Optic Neuritis in the Older Chinese Population: A 5-Year Follow-Up Study

Table 2

Factors for visual prognosis in middle-aged and elderly patients with optic neuritis.

Factors		Number of patients with final VA < 20/400	Number of patients with final VA ≥ 20/400	value
Initial BCVA	>20/400	3	16	0.001
	<20/400	35	22
Sex	Male	15	17	NS
	Female	23	21
Age	<65	31	37	NS
	≥65	7	1
Laterality	Unilateral	24	29	NS
	Bilateral	14	9
Initial disc appearance	Normal	23	21	NS
	Swollen	14	16
Systemic association	Normal	20	23	NS
	Abnormal	10	11
CSF	Normal	10	12	NS
	Abnormal	13	11
Serum AQP4-Ab status	Seropositive	7	3	NS
	Seronegative	17	22
Orbital MRI	Normal	4	5	NS
	Abnormal	22	22
Brain MRI	Normal	11	15	NS
	Abnormal	13	11
pRNLF	Average	64.00 ± 12.91	68.58 ± 18.70	NS
	Superior	69.52 ± 20.72	79.23 ± 32.63	NS
	Nasal	59.60 ± 9.39	60.35 ± 10.00	NS
	Inferior	72.88 ± 23.53	83.88 ± 30.37	NS
	Temporary	50.85 ± 15.81	52.92 ± 10.15	0.045

BCVA: best corrected visual acuity; CF: count finger; CSF: cerebrospinal fluid; AQP4-Ab: anti-aquaporin-4 antibody; MRI: magnetic resonance imaging; pRNLF: peripapillary retinal nerve fibre layer, NS: nonsignificant; .