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Journal of Ophthalmology
Volume 2017, Article ID 4271671, 8 pages
Clinical Study

The Effect of Perioperative Topical Ketorolac 0.5% on Macular Thickness after Uneventful Phacoemulsification

1Department of Ophthalmology, Erzurum Regional Training and Research Hospital, Erzurum, Turkey
2Department of Ophthalmology, Ankara Ataturk Training and Research Hospital, Faculty of Medicine, Yildirim Beyazit University, Ankara, Turkey
3Department of Ophthalmology, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey
4Department of Ophthalmology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
5Department of Ophthalmology, Malatya Training and Research Hospital, Malatya, Turkey

Correspondence should be addressed to Derya Dal; moc.oohay@ladayred

Received 13 April 2017; Accepted 6 July 2017; Published 23 November 2017

Academic Editor: Terri L. Young

Copyright © 2017 Derya Dal et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. To evaluate the effects of topical 0.5% ketorolac treatment combined with topical steroids on macular thickness in cases who had uneventful phacoemulsification surgery. Methods. 58 eyes of 58 consecutive cases were included. The mean foveal thickness (MFT), parafoveal thickness (ParaFT), and perifoveal thickness (PeriFT) measurements were performed with optical coherence tomography (RTVue-100, Optovue, Fremont, CA, USA) preoperatively and at postoperative 1 week, 1 month, and 2 months. All cases received topical 0.1% dexamethasone postoperatively. Randomly selected cases additionally received topical 0.5% ketorolac, which started 2 days prior to surgery. Cases who received both topical steroids and ketorolac formed group 1 and subjects who received only topical steroids formed group 2. Results. The increase in mean MFT at the 1st week, 1st month, and 2nd months after surgery in group 1 was significantly lower than group 2 (, , and , resp.). In group 1, the increase in mean ParaFT and PeriFT was significantly lower than group 2 at the 1st and 2nd months of the surgery ( for all variables). Conclusions. Topical ketorolac combined with steroids is highly efficacious in order to prevent increment in thickness on each part of the macula even after an uneventful phacoemulsification surgery comparing to steroid monotheraphy.