Research Article

The Protective Effects of αB-Crystallin on Ischemia-Reperfusion Injury in the Rat Retina

Figure 4

The level of MDA and NO and activities of T-SOD were showed (). The level of MDA and NO was higher in I/R + vehicle and I/R + αB-crystallin groups than those in sham group, but was significantly lower in I/R + αB-crystallin group than in I/R + vehicle group at 24 h after I/R () (a, b). Activity of T-SOD in I/R + vehicle and I/R + αB-crystallin groups became significantly lower than those of sham group at 24 h after I/R (); activity of T-SOD in I/R + vehicle group was significantly higher than those in I/R + αB-crystallin group at 24 h after I/R () (c). In the content of MDA, NO, and T-SOD, there was no significant difference between I/R + vehicle and I/R + αB-crystallin groups () at 1 w . ; . I/R: ischemia/reperfusion; MDA: malondialdehyde; NO: nitric oxide T-SOD: total-superoxide dismutase.
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