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Journal of Ophthalmology
Volume 2017, Article ID 8248710, 9 pages
Clinical Study

Short-Term Clinical Results of Ab Interno Trabeculotomy Using the Trabectome with or without Cataract Surgery for Open-Angle Glaucoma Patients of High Intraocular Pressure

1Doheny Image Reading Center, Doheny Eye Institute, Los Angeles, CA, USA
2Department of Ophthalmology, David Geffen School of Medicine, Los Angeles, CA, USA

Correspondence should be addressed to Brian A. Francis; gro.ynehod@sicnarfb

Received 27 August 2016; Revised 19 December 2016; Accepted 19 February 2017; Published 18 April 2017

Academic Editor: Chelvin Sng

Copyright © 2017 Handan Akil et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To assess the safety and efficacy of Trabectome procedure in patients with preoperative intraocular pressure (IOP) of 30 mmHg or higher. Methods. All patients who had underwent Trabectome stand-alone or Trabectome combined with phacoemulsification were included. Survival analysis was performed by using Kaplan-Meier, and success was defined as IOP ≤ 21 mmHg, 20% or more IOP reduction from baseline for any two consecutive visits after 3 months, and no secondary glaucoma surgery. Results. A total of 49 cases were included with an average age of 66 (range: 13–91). 28 cases had Trabectome stand-alone and 21 cases had Trabectome combined with phacoemulsification. Mean IOP was reduced from a baseline of 35.6 ± 6.3 mmHg to 16.8 ± 3.8 mmHg at 12 months (), while the number of medications was reduced from 3.1 ± 1.3 to 1.8 ± 1.4 (). Survival rate at 12 months was 80%. 9 cases required secondary glaucoma surgery, and 1 case was reported with hypotony at day one, but resolved within one week. Conclusion. Trabectome seems to be safe and effective in patients with preoperative IOP of 30 mmHg or greater. Even in this cohort with high preoperative IOP, the end result is a mean IOP in the physiologic range.