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Journal of Ophthalmology
Volume 2017 (2017), Article ID 8597629, 6 pages
Research Article

Pattern Visual Evoked Potential Changes in Diabetic Patients without Retinopathy

1Department of Ophthalmology, Dr. Nafiz Korez Sincan State Hospital, Ankara, Turkey
2Department of Ophthalmology, Ankara Training and Research Hospital, Ankara, Turkey
3Department of Family Medicine, Yildirim Beyazit University Faculty of Medicine, Ankara, Turkey

Correspondence should be addressed to Ozgur Balta

Received 7 December 2016; Revised 9 February 2017; Accepted 20 February 2017; Published 14 March 2017

Academic Editor: Lisa Toto

Copyright © 2017 Ozgur Balta et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To assess the different check sizes of pattern visual evoked potential (PVEP) in diabetic patients without retinopathy according to HbA1c levels and diabetes duration. Methods. Fifty-eight eligible patients with type 2 diabetes mellitus and 26 age- and sex-matched healthy controls were included in the study. Only the right eye of each patient was analyzed. All of the patients underwent a comprehensive ophthalmic examination, and the PVEPs were recorded. Results. There was a statistically significant difference in P100 latency in 1-degree check size and in N135 latency in 2-degree check size between controls and patient groups which have different HbA1c levels. There were statistically significant, positive, and weak correlations with diabetes duration and P100 latency in 7-minute and 15-minute check sizes and N135 latency in 15-minute check size. Conclusions. It was showed that there were prolongations in P100 latency only in 1-degree check size and in N135 only in 2-degree check size in diabetic patients without retinopathy. There was statistically significant correlation between diabetes duration and P100 and N135 latencies in different check sizes.