The Degeneration and Apoptosis Patterns of Cone Photoreceptors in rd11 Mice

Figure 4

Costaining for L-opsin or S-opsin and PNA in C57BL/6J control and rd11 retina. Immunofluorescence of retinal cryosections from C57BL/6J control and P14, P28, and P42 rd11 mice labeled with L-opsin or S-opsin and PNA lectin. (a) Costaining of L-opsin and PNA. (b) Costaining of S-opsin and PNA. Cells were counterstained with DAPI. Arrows indicate cones with colocalization of PNA and either L- or S-opsin. Red: L-opsin or S-opsin, green: PNA, and blue: DPAI. OS: outer segments; IS: inner segments; ONL: outer nuclear layer; OPL: outer plexiform layer. retina per group.

(a)

(b)