Mapping the Structure-Function Relationship in Glaucoma and Healthy Patients Measured with Spectralis OCT and Humphrey Perimetry

Figure 1

(a) Spatial correspondence between the measuring points of threshold sensitivity in the automatized perimetry (Humphrey, 24-2 program) and the macular thickness map (Spectralis OCT). (b) Graphic scheme of the first nonparametric spatial regression model. The measurements of threshold sensitivity in each of the 16 central points of the visual field are regressed on the macular thickness of the four surrounding areas. (c) Graphic scheme of the second nonparametric spatial regression model. The measurements of threshold sensitivity in each of the 34 central points of the visual field are regressed on the macular thickness of either the four surrounding areas for the 16 central points or the closest one or two areas (depending on the position) for the 18 most eccentric points. (d) Graphic scheme of the third nonparametric spatial regression model. Two separate regressions were performed: the measurements of threshold sensitivity in each of the 4 central points of the visual field on the macular thickness of the four surrounding areas (red) and the measurements in each of the other 30 points (green) on the 4, 2, or 1 (depending on the position) closest areas.

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