Clinical Study

Early Changes in Visual Quality and Corneal Structure after DMEK: Does DMEK Approach Optical Quality of a Healthy Cornea?

Table 2

Visual quality parameters as obtained with Oculus Pentacam of corneas undergoing Descemet membrane endothelial keratoplasty (DMEK) measured preoperative and at 1 month and at 6 months postoperative.

Quality parameterPreoperative1 month postoperativeP (preoperative vs 1 month postoperative)6 months postoperativeP (1 month vs 6 months postoperative)

Anterior cornea
Central density39.81 (10.99)33.60 (13.87)0.06924.32 (2.92)0.006
0–2 mm density43.83 (10.50)35.60 (12.16)0.04525.21 (5.40)0.035
Total density41.06 (10.43)38.40 (10.03)0.48929.25 (6.52)0.029
Km43.83 (2.03)43.13 (1.86)0.28142.85 (1.50)0.607
RMS HOA (µm)1.19 (0.52)1.66 (0.79)0.2491.50 (1.11)0.317
RMS LOA (µm)3.36 (1.23)4.73 (1.67)0.0263.86 (2.24)0.427
RMS total (µm)3.60 (1.28)5.04 (1.77)0.0224.39 (2.23)0.522

Posterior cornea
0–2 mm density27.70 (4.20)22.07 (7.45)0.00617.60 (2.83)0.010
Total density29.06 (4.56)26.26 (5.44)0.21423.38 (3.52)0.128
Km−5.84 (0.23)−6.80 (0.67)0.005−6.52 (0.39)0.217
RMS HOA (µm)0.69 (0.34)0.69 (0.26)0.8280.47 (0.13)0.015
RMS LOA (µm)1.71 (1.08)1.54 (0.56)0.8701.04 (0.29)0.020
RMS total (µm)1.86 (1.11)1.71 (0.57)0.7031.15 (0.29)0.015

Bold letters indicate . Asterisk marks Bonferroni values <0.007. DMEK, Descemet membrane endothelial keratoplasty; Km, mean keratometry; RMS, root mean square; HOA, high-order aberrations; LOA, low-order aberrations; µm, microns.