Journal of Ophthalmology / 2018 / Article / Tab 2 / Research Article
The Association between Female Reproductive Factors and Open-Angle Glaucoma in Korean Women: The Korean National Health and Nutrition Examination Survey V Table 2 Univariate and age-adjusted logistic regression analyses for the association between factors and open-angle glaucoma in all participants and participants with natural menopause.
All participants Univariate Age-adjusted OR (95% CI) valueOR (95% CI) valueAge, per year 1.04 (1.03–1.06) <0.001 Age at menarche, years 13–16 years Reference 0.145 Reference 0.126 ≤12 years 1.03 (0.53–2.03) 1.39 (0.70–2.74) ≥17 years 1.29 (1.00–1.67) 0.80 (0.62–1.04) Early menopause (<45 years) (%) 1.56 (1.03–2.35) 0.035 1.41 (0.91–2.16) 0.122 Parity 1.15 (1.10–1.20) <0.001 1.01 (0.96–1.07) 0.627 Reproductive years 1.00 (0.97–1.03) 0.804 1.01 (0.98–1.04) 0.396 Hypertension (%) 2.10 (1.59–2.76) <0.001 1.33 (0.99–1.80) 0.015 Diabetes mellitus (%) 2.17 (1.53–3.07) <0.001 1.54 (1.07–2.22) 0.021 Oral contraceptives use (ever, %) 0.89 (0.63–1.26) 0.515 0.75 (0.52–1.06) 0.099 ≥3 years 1.06 (0.48–2.36) 0.882 0.94 (0.42–2.11) 0.875 Hormone replacement (ever, %) 0.90 (0.58–1.39) 0.625 0.90 (0.58–1.39) 0.623 Myopia (%) 1.21 (0.90–1.64) 0.210 1.69 (1.24–2.31) 0.001 Body mass index 0.99 (0.95–1.03) 0.552 0.98 (0.95–1.02) 0.390 Lactation (ever, %) 1.21 (0.85–1.83) 0.259 0.68 (0.45–1.04) 0.106 Participants with natural menopause Age, per year 1.04 (1.02–1.05) <0.001 Age at menarche, years 13–16 years Reference 0.335 Reference 0.041 ≤12 years 1.70 (0.74–3.90) 1.94 (0.85–4.47) ≥17 years 0.94 (0.70–1.26) 0.79 (0.59–1.06) Early menopause (<45 years) (%) 2.40 (1.50–3.83) <0.001 1.88 (1.11–3.19) 0.019 Number of parity 1.08 (1.03–1.14) 0.003 1.01 (0.95–1.07) 0.808 Reproductive years, years 1.00 (0.96–1.03) 0.846 1.01 (0.98–1.05) 0.439 Hypertension (%) 1.57 (1.15–2.13) 0.005 1.24 (0.89–1.73) 0.200 Diabetes mellitus (%) 1.47 (0.95–2.28) 0.085 1.27 (0.82–1.98) 0.114 Oral contraceptives use (ever, %) 0.82 (0.56–1.19) 0.286 0.80 (0.55–1.16) 0.239 ≥3 years 1.04 (0.45–2.40) 0.936 1.02 (0.44–2.37) 0.961 Hormone replacement (ever, %) 0.86 (0.54–1.37) 0.522 1.06 (0.66–1.70) 0.805 Myopia (%) 1.53 (1.06–2.21) 0.022 1.59 (1.10–2.32) 0.015 Body mass index 0.98 (0.94–1.03) 0.486 0.99 (0.94–1.03) 0.587 Lactation (ever, %) 0.92 (0.53–1.60) 0.775 0.68 (0.38–1.19) 0.176
CI = confidence interval.