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Journal of Ophthalmology
Volume 2018, Article ID 3490962, 10 pages
Research Article

The Comparison of Regional RNFL and Fundus Vasculature by OCTA in Chinese Myopia Population

1Department of Ophthalmology, Hunan Clinical Research Center of Ophthalmic Disease, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
2Department of Ophthalmology, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, The Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China

Correspondence should be addressed to Bing Jiang; nc.ude.usc@bgnaijrd

Received 24 September 2017; Revised 3 December 2017; Accepted 18 December 2017; Published 31 January 2018

Academic Editor: Katarzyna J. Witkowska

Copyright © 2018 Yuanjun Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To determine the correlations between peripapillary vessel density, retinal nerve fibre layer (RNFL) thickness, and myopic indices at retina quadrants with optical coherence tomography angiography (OCTA) in Chinese. Methods. Fifty-six subjects with a mean spherical equivalent (MSE) of −3.63 ± 0.29 D were included. Peripapillary RNFL thickness and retinal vessel density in four sectors (superior, nasal, inferior, and temporal quadrants) were determined by OCTA, and correlations of the main outcomes were analyzed. Results. Negative correlations were found between the peripapillary RNFL thickness and axial length (AL) at superior (, ) and inferior (, ) quadrants. There was a significant positive correlation with spherical equivalent (SE) at the corresponding quadrants as well as at the nasal quadrant (, ; , ; and , , resp.). Peripapillary retinal vessel density was also negatively correlated with AL at the nasal quadrant (, ), and only at the nasal quadrant, there was a positive correlation between the peripapillary vessel density and SE (, ). Conclusions. The degree of myopia and elongation of AL were negatively correlated with peripapillary RNFL thickness at superior and inferior quadrants and with peripapillary retinal vessel density at the nasal quadrant.