Clinical Study
Clinical Efficacy of Platelet-Rich Plasma in the Treatment of Neurotrophic Corneal Ulcer
Table 2
Clinical classification of neurotrophic keratopathy based on the Mackie classification.
| Stage | Clinical findings |
| I | Corneal epithelial irregularity | Gaule spots | Superficial punctuate keratopathy | Increase viscosity of tear mucus | Decrease break-up time | Superficial corneal neovascularization | Stromal scarring | Dellen |
| II | Persistent corneal epithelial defect with smooth and rolled epithelium edges | Descemet’s membrane folds | Stroma swelling | Anterior chamber inflammatory reaction (±hypopyon) |
| III | Corneal ulcer | Stromal melting | Corneal perforation |
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